منابع مشابه
Codon and Amino Acid Usage Are Shaped by Selection Across Divergent Model Organisms of the Pancrustacea
In protein-coding genes, synonymous codon usage and amino acid composition correlate to expression in some eukaryotes, and may result from translational selection. Here, we studied large-scale RNA-seq data from three divergent arthropod models, including cricket (Gryllus bimaculatus), milkweed bug (Oncopeltus fasciatus), and the amphipod crustacean Parhyale hawaiensis, and tested for optimizati...
متن کاملDivergent Platforms
Models of electoral competition between two opportunistic, office-motivated parties typically predict that both parties become indistinguishable in equilibrium. I show that this strong connection between the office motivation of parties and their equilibrium choice of identical platforms depends on two possibly false assumptions: 1. Issue spaces are uni-dimensional and 2. Parties are unitary ac...
متن کاملEvidence of Divergent Amino Acid Usage in Comparative Analyses of R5- and X4-Associated HIV-1 Vpr Sequences
Vpr is an HIV-1 accessory protein that plays numerous roles during viral replication, and some of which are cell type dependent. To test the hypothesis that HIV-1 tropism extends beyond the envelope into the vpr gene, studies were performed to identify the associations between coreceptor usage and Vpr variation in HIV-1-infected patients. Colinear HIV-1 Env-V3 and Vpr amino acid sequences were ...
متن کاملApplication of Gene Expression Trajectories Initiated from ErbB Receptor Activation Highlights the Dynamics of Divergent Promoter Usage
Understanding how cells use complex transcriptional programs to alter their fate in response to specific stimuli is an important question in biology. For the MCF-7 human breast cancer cell line, we applied gene expression trajectory models to identify the genes involved in driving cell fate transitions. We modified trajectory models to account for the scenario where cells were exposed to differ...
متن کاملGrammar Is Grammar and Usage Is Usage
A number of disparate approaches to language, ranging from cognitive linguistics to stochastic implementations of optimality theory, have challenged the classical distinction between knowledge of language and use of language. Supporters of such approaches point to the functional motivation of grammatical structure, language users’ sensitivity to the frequency of occurrence of grammatical elemen...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 1981
ISSN: 0028-0836,1476-4687
DOI: 10.1038/291608g0